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Glaucoma and neuroprotection: C-Type Natriuretic Peptide and opioid receptors

Submitted by Bailey on Tue, 02/15/2011 - 10:20pm

I have been coming across a few articles and studies dealing with c-type natriuretic peptides (CNP) and opioid receptors as they potentially  relate to glaucoma, IOP and neuroprotection. While I don't have enough to go on in order to build any cogent arguments, I will present what I have found as a matter of interest. As a quick preview, it seems that CNP has neuroprotective effects..

Brian A. Francis, MD in CA, USA Supports Home Eye Pressure Monitoring

Submitted by FitEyesAdmin on Mon, 02/14/2011 - 10:26pm

A FitEyes member has recommended Brian A. Francis, MD, MS after trying six other glaucoma specialists who were not to her liking. The FitEyes member has just purchased her own tonometer and will be using it with the full support of Dr. Francis.

 

Title: Associate Professor of Clinical Ophthalmology

Department: Department of Ophthalmology

Locations: Doheny Eye Institute

Areas of Treatment:

Cataract as related to glaucoma? Recommendation for surgery? Alternatives?

Submitted by BobDobbs on Fri, 02/11/2011 - 2:01pm

Hi.  Seemingly as soon as I started using glaucoma eyedrops, I started getting cataract in my right eye.  Then the left eye, and both are very bad now.  I am about to break down and get lens-replacement surgery I guess, as I know if no alternative at this point.

Possibly NAC eyedrops (Can-C) would have worked if I started them early enough, but I didn't. 

Do you know of a glaucoma specialist in Los Angeles?

Submitted by BobDobbs on Fri, 02/11/2011 - 1:51pm

Does anyone know who are the best glaucoma specialists in Los Angeles?

There are both USC and UCLA centers here.  UCLA has the Jules Stein Eye Institute and I'm not sure what USC has.  So there is not shortage of glaucoma specialists here, but ....

who is supportive of self-tonometry?

who is supportive of nutritional approaches, etc.?

 

Please help ASAP if you know of someone.  Thanks!

Dr. Marc Rose -- Los Angeles, CA & Costa Mesa, CA

Submitted by BobDobbs on Fri, 02/11/2011 - 1:47pm

Dr. Marc Rose is a really good, upbeat, friendly and supportive opthamologist.  As he has said it to me, he supports ANYTHING that brings your IOP down.  He advocates a nutritional approach for patients who will listen, utilizing foods and supplements.  He wrote me a prescription for a tonometer and is supportive of that, although I have yet to find the budget.

Effects of meditation, alcohol, and exercise on IOP

Submitted by bstruss on Wed, 02/09/2011 - 10:23pm

Here is a recent thread on Fiteyes newsgroup

From Diane:

I have been doing self-tonometry every day for the past 8 months or so with the Reichert 7 cr.  I have experimented with different types of exercise, both aerobic and weigh bearing, meditation, visualization, deep breathing, etc.  It seems getting my IOP lowered through any of these measures is hit or miss.  Sometimes my pressure winds up going higher, even when I am feeling completely relaxed and peaceful.

Yale using new techniques to treat glaucoma

Submitted by liftaddict on Sun, 02/06/2011 - 6:56pm

Just saw this article in the NewHavenRegister.  Dr. Nils Loewen of yale Eye Center uses a treatment for advanced cases  The article states " The second procedure involves inserting a gold shunt to drain fluid and is only used in advanced cases.  Loewen said it"s somthing that i'm particularly excited about because we're are only one of six centers in the US to offer this. 

A small piece of gold is inserted under the eyelid, which " shunts fluid into a previously unutilized area, the supra-choroidal space"

On the cover of page B3

 

I am loathe to take glaucoma eye drops because of the potential side effects

Submitted by dave on Thu, 02/03/2011 - 10:52am

 A new FitEyes.com member wrote:

Hello, I have a query I would like some advice on.  I have only just joined and this is all a new area for me so please forgive me if i'm covering old ground.  I was diagnosed with early stage Glaucoma in one eye this week.  I have been given Xalatan drops to take.  I am loathe to take these because of the side effects.
 
Do I need to take these?  Are there other alternatives and methods?  Any advice would be much appreciated.
 
Thank you
 
Hi and welcome to FitEyes.
 

I don't think it's prudent to be telling each other we CAN restore lost vision

Submitted by lois_rochelle on Fri, 01/28/2011 - 4:06pm

I read a post here on FitEyes.com regarding trabeculotomy success or failure. I've NOT had a trabeculotomy.  About 6 months ago, one of my several doctors suggested that this operation might be in my future, and I did some reading.  There's an excellent book on glaucoma, What Your Doctor May Not Tell You About Glaucoma, by Gregory K. Harmon M.D. & Nancy Intrator, published in 2004, that has the following to say about trabeculotomy success rates (p. 180):

If the IOP readings are ever high it proves that they do go that high

Submitted by dave on Fri, 01/28/2011 - 1:57pm

From a reader:

The doctor looked at my self-tonometry eye pressure data I brought with me. But he did not give my data much credence. He said if the  intraocular pressure readings are ever high then that shows that they do go that high. He is quite intimidating.

The assumption by the doctor is that he must target his treatment at the maximum intraocular pressure peak no matter how short it lasted, or how infrequent it is or what caused the IOP to rise.

Ophthalmologists are not yet familiar with the concept of the ocular white coat syndrome (white coat ocular hypertension). Our self-tonometry data may show that our IOP is lower outside the doctor's office than inside the office. Many of us believe this is an important consideration and a few doctors are starting to pay close attention to this information.

But reading your doctor's intimidating response gave me an idea...

Conducting research on relaxation techniques to lower eye pressure

Submitted by Jerrold Ehrlich on Fri, 01/28/2011 - 1:35pm

I am an attorney and my spouse is a glaucoma patient. In the past I have volunteered some of my time to help FitEyes look into questions related to research projects and other activities related to the non-medical treatment of elevated 
intraocular pressure. I would like to share my feedback in two areas:

  • our outstanding questions
  • what we know so far.

Here are some of the outstanding questions that apply directly to the project presently under discussion, which is related to using a relaxation technique to lower intraocular pressure.

How do I spend my day off? On FitEyes, of course!

Submitted by dave on Mon, 01/24/2011 - 10:34pm

Sometimes I wonder where all my time goes. I know I volunteer a lot of time to FitEyes that is unrelated to working with my clients or doing other things I "have" to do. So I did a quick check of where my time went on my recent "day off." Here's what it looked like:

 

1 hour emails (mostly related to FitEyes)

1 hour discussing new FitEyes website work with a developer

3 hours researching backup and storage solutions for the FitEyes website (long overdue)

1 hour to get a replacement computer part

Tonometer in use!

Submitted by dave on Mon, 01/24/2011 - 10:07pm

I just received the email below. While I love these emails and each one makes me smile, this is a fairly typical response I see when someone receives their new Reichert tonometer. Keep in mind that the expectation from both of us is that we will have a telephone call when the person's new tonometer arrives and I will explain how to use it. The surprising result is that quite often I don't have to explain anything! That's how easy these Reichert tonometers are to use . This is true even for someone who is not good with technology.

Here's the email that just came today:

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