Research has shown that stress can physically reshape the brain, causing both extensive and long-lasting damage to the human brain. Brain cells can shrink and the connections between neurons can decrease. In short, stress causes big changes to the human nervous system. In 2008, new knowledge regarding the effects of short-term stress were measured at University of California, Irvine, and breakthrough research on the effects of long-term, chronic stress were conducted at the University of Wisconsin, Milwaukee.
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