glaucoma eye drops

Glaucoma eye drop with the least side effects

Submitted by doumyee on Sun, 09/08/2013 - 7:26pm

Hi! Community !

I have been diagnosed glaucoma(I.O.P is 16-19) but still losing optic nerve cells.

So my target I.O.P is 12-13 according to my eye doctor, hopfully my I.O.P is under controlling(not losing optic nerve cells).

I have researched the glaucoma eye drops(Beta Blocker) currently available in the market. 

Anyone knows eye drop with minimal side effects?  I have just found out  timolol causes cancer in long term use.

the list of eye drops found in research:





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Glaucoma Educational Art Project

Submitted by wesleyray on Tue, 06/26/2012 - 7:31pm

At 57, 7 years after discovering I have Glaucoma I am considering Glaucoma filtration surgery as I'm concerned with the effects the Azopt and Lumigan drops have on my system. I have always maintained a healthy diet (no red meat in 35 years). For the past 7 years I have had acupuncture treatments weekly ( my acupuncturist has successfully treated her father, who has Glaucoma,  keeping his pressure down without drops or surgery). My pressures have been around 13-15 (tested by my Ophthalmologist only).

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Top 10 Reasons For Not Taking Your Glaucoma Eye Drops

Submitted by JohnJohn on Fri, 07/30/2010 - 3:32pm


Dr. Amy Hennessy of The Johns Hopkins Bloomberg School of Public Health, in Baltimore stated "Getting eyedrops into the eye is not the same as asking a patient to swallow a pill, or use a skin cream. It's easier said than done."


Consider 64% of glaucoma patients state they follow physcian's instructions "Extremely closely". Yet :

Nitric Oxide compound lowers eye pressure more than glaucoma drugs like Xalatan alone

Submitted by dave on Mon, 04/26/2010 - 8:03pm

 A Novel Nitric Oxide Releasing Prostaglandin Analog, NCX 125, Reduces Intraocular Pressure in Rabbit, Dog, and Primate Models of Glaucoma




Purpose: Nitric oxide (NO) is involved in a variety of physiological processes including ocular aqueous humor dynamics by targeting mechanisms that are complementary to those of prostaglandins. Here, we have characterized a newly synthesized compound, NCX 125, comprising latanoprost acid and NO-donating moieties.

Methods: NCX 125 was synthesized and tested in vitro for its ability to release functionally active NO and then compared with core latanoprost for its intraocular pressure (IOP)-lowering effects in rabbit, dog, and nonhuman primate models of glaucoma.

Results: NCX 125 elicited cGMP formation (EC50 = 3.8 ± 1.0 μM) in PC12 cells and exerted NO-dependent iNOS inhibition (IC50 = 55 ± 11 μM) in RAW 264.7 macrophages. NCX 125 lowered IOP to a greater extent compared with equimolar latanoprost in: (a) rabbit model of transient ocular hypertension (0.030% latanoprost, not effective; 0.039% NCX 125, ∆max = −10.6 ± 2.3 mm Hg), (b) ocular hypertensive glaucomatous dogs (0.030% latanoprost, ∆max= −6.7 ± 1.2 mm Hg; 0.039% NCX 125, ∆max = −9.1 ± 3.1 mm Hg), and (c) laser-induced ocular hypertensive non-human primates (0.10% latanoprost, ∆max = −11.9 ± 3.7 mm Hg, 0.13% NCX 125, ∆max = −16.7 ± 2.2 mm Hg). In pharmacokinetic studies, NCX 125 and latanoprost resulted in similar latanoprost-free acid exposure in anterior segment ocular tissues.

Conclusions: NCX 125, a compound targeting 2 different mechanisms, is endowed with potent ocular hypotensive effects. This may lead to potential new perspectives in the treatment of patients at risk of glaucoma.


Glaucoma eye drops and depression

Submitted by 3287nest on Wed, 02/03/2010 - 8:46am

I am using eyedrops: timolol maleate and pilocarpine.  After a week on both, I'm feeling uncharacteristically  low and negative.  Both list depression as side effects.  I'm wondering what experience others have had re: eyedrops and depression.   Know any remedies?  I hope, I'll be off these two in a couple of weeks!  They also blur my vision.


Travatan Z makes my vision cloudy

Submitted by 3287nest on Mon, 09/14/2009 - 9:27pm

Travatan Z makes my vision so cloudy that I can hardly see.   Cloudy is not really the word for it:  it's more like the kind of vision you'd get from a combination of cataracts and a migraine headache.. What experience have others had with it?


Score Another One for Self-Tonometry

Submitted by Anonymous (not verified) on Tue, 09/08/2009 - 11:59am

Well, I’ve had another interesting observation.

For the past several years, I’ve been taking my prostaglandin analogue, Travatan Z, at night right before going to bed as directed by my ophthalmologist.  However, having been startled by the high levels of my nocturnal IOP, I started researching ways to lower it.  

Free Glaucoma Eye Drops for Newly Unemployed Americans

Submitted by dave on Sat, 08/08/2009 - 1:17pm

The Pfizer MAINTAIN program helps eligible people in financial need continue to get their Pfizer medicines — including the glaucoma drug Xalatan® — if they have recently become unemployed and do not have prescription coverage. Beneficiaries of the program will get their Pfizer medicines for free for up to a year or until they become re-insured (whichever comes first).


Individuals and their immediate family members are eligible for this program if:


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