The role of SIRT1 in ocular aging and glaucoma

The role of SIRT1 in ocular aging.

The sirtuins are a family of enzymes that regulate DNA expression. The sirtuin family helps regulate the lifespan of diverse organisms. Humans have seven different sirtuins (SIRT1-7). This study suggests that SIRT1 may provide protection against diseases related to oxidative stress-induced ocular damage, including cataract, age-related macular degeneration, and optic nerve degeneration in glaucoma patients.


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