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Glaucoma and Alpha Lipoic Acid

Submitted by Agnes on Sat, 10/10/2009 - 11:59am


A clear fluid flows in and out of the space at the front of the eye, nourishing nearby tissues. Glaucoma causes the fluid to pass through too slowly or to stop draining altogether. As the fluid builds up, the pressure inside the eye increases, causing damage to the optic nerve and vision loss.

Glaucoma and Alpha Lipoic Acid - Forty-five patients with stage I and II open-angle glaucoma (OAG) were administered either 75 mg of alpha-lipoic acid for 2 months or 150 mg for 1 month. A control group of 31 patients with OAG were administered only local hypotensive therapy. The greatest improvement of biochemical parameters (gamma-glutamyl transpeptidase and non-protein SH-groups), visual function, and the coefficient of efficacy of liquid discharge was observed in the patients administered the higher dose of alpha-lipoic acid. Preliminary evidence indicates that 150 mg of alpha lipoic acid, taken daily for one month, significantly improves visual function in people with glaucoma.*

* Filina AA, Davydova NG, Endrikhovskii SN, et al. Lipoic acid as a means of metabolic therapy of open-angle glaucoma. Vestn Oftalmol 1995;111:6-8.

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