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Discovery of a new mechanism that can lead to blindness

medicalnewstoday eye health - Fri, 10/17/2014 - 3:00am
An important scientific breakthrough by a team of IRCM researchers led by Michel Cayouette, PhD, is being published today by The Journal of Neuroscience.
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How safe are human embryonic stem cell transplants?

medicalnewstoday eye health - Wed, 10/15/2014 - 2:00am
Although the potential therapeutic uses of human embryonic stem cells have been known since 1981, until now, the long-term safety of these transplantations had not been assessed.
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World watches as grandfather from Malawi has his sight restored live online

medicalnewstoday eye health - Fri, 10/10/2014 - 4:00am
A blind man's sight-restoring operation was broadcast live around the world at 1.30pm(BST) October 8, 2014 from a hospital in Malawi.
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Over 123 million lost workdays per year caused by blindness or eye diseases according to new pan-European health economic study

medicalnewstoday eye health - Fri, 10/10/2014 - 3:00am
The European Forum Against Blindness (EFAB) has revealed the results of an 11-country study (an extension to the data reported last year covering six countries) which reports on the economic impact...
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Nano-drug for dry eyes brings relief with less trouble

medicalnewstoday eye health - Thu, 10/09/2014 - 5:00am
Drug-infused nanoparticles applied only once a week appear to be as effective at relieving dry eyes as the standard three-drops-a-day medication, according to a new study.
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Pitt researchers receive $1.25 million from Defense Department to make whole-eye transplantation a reality

medicalnewstoday eye health - Thu, 10/09/2014 - 4:00am
University of Pittsburgh School of Medicine researchers have been awarded $1.25 million from the U.S.
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Squints can be treated at any age - Examination of children important in their first year of life

medicalnewstoday eye health - Thu, 10/09/2014 - 4:00am
Around four per cent of all newborn children have a squint. In about 50 per cent of cases, this can be corrected with appropriate glasses, however the other half require treatment for their squint...
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Detergent pods should be kept out of reach to help prevent ocular injury

medicalnewstoday eye health - Thu, 10/09/2014 - 3:00am
Liquid laundry and dishwasher detergent pods are an emerging source of chemical exposure in children.
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UK data presented at EURETINA 2014 showcase efficacy of EYLEA in clinical practice for the treatment of wet age-related macular degeneration

medicalnewstoday eye health - Sun, 10/05/2014 - 2:00am
Bayer HealthCare reports that data have been presented at the 14th EURETINA congress in London, showcasing the efficacy of EYLEA® (aflibercept solution for injection) for the treatment of wet...
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Discovery of special stem cells in the eye could lead to better treatments for blindness

medicalnewstoday eye health - Sat, 10/04/2014 - 2:00am
Scientists at the University of Southampton have discovered that a region on the front surface of the eye harbours special stem cells that could treat blinding eye conditions.
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Sildenafil for erectile dysfunction could affect vision of genetically susceptible users

medicalnewstoday eye health - Thu, 10/02/2014 - 3:00am
Sildenafil, the active ingredient in the erectile dysfunction drug Viagra®, could cause unusual visual responses in people who carry a common mutation for eye disease and may have long-term...
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A Comparison of Optic Nerve Head Topographic Measurements by Stratus OCT in Patients With Macrodiscs and Normal-sized Healthy Discs

Journal of Glaucoma - Tue, 09/30/2014 - 11:00pm
Purpose:To evaluate and compare optic nerve head parameters and retinal nerve fiber layer (RNFL) thickness between large discs and normal-sized vital discs using Stratus optical coherence tomography (OCT). Methods:A total of 293 healthy eyes (145 with macrodisc and 148 with normal-sized disc) were enrolled in the study. After a complete ophthalmic evaluation, measurement of optic nerve head parameters and RNFL thickness using OCT was performed in all subjects. Optic disc areas larger than 2.80 mm2 were accepted as macrodiscs. All OCT parameters were compared between normal-sized discs and macrodiscs. Results:Participants’ mean age was 46.5±10.6 years (range, 13 to 74 y). Average optic disc areas were 2.19±0.29 and 3.02±0.29 mm2 in the normal and the macrodisc groups, respectively. The...
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Diagnostic Validity of Macular Ganglion Cell-Inner Plexiform Layer Thickness Deviation Map Algorithm Using Cirrus HD-OCT in Preperimetric and Early Glaucoma

Journal of Glaucoma - Tue, 09/30/2014 - 11:00pm
Conclusions:mGCIPL thickness deviation map showed good diagnostic ability in detecting preperimetric and early glaucoma, and it was comparable with pRNFL thickness deviation map. Our findings suggest that it can be an important parameter in detecting subtle glaucomatous structural change. (Source: Journal of Glaucoma)
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Comparison of Fluctuations of Intraocular Pressure Before and After Selective Laser Trabeculoplasty in Normal-tension Glaucoma Patients

Journal of Glaucoma - Tue, 09/30/2014 - 11:00pm
Conclusions:SLT treatment was shown to significantly lower IOP and decrease IOP fluctuations during the nocturnal periods in NTG patients. These effects might be important to prevent the progression of NTG. (Source: Journal of Glaucoma)
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Accuracy of Macular Ganglion-Cell Complex Thickness to Total Retina Thickness Ratio to Detect Glaucoma in White Europeans

Journal of Glaucoma - Tue, 09/30/2014 - 11:00pm
Purpose:The aim of this study was to evaluate the diagnostic accuracy of macular ganglion-cell complex (GCC) thickness to total retinal thickness ratio (G/T ratio), a parameter found particularly accurate in Japanese eyes to detect glaucoma and recently proposed for the RTVue-100 Fourier-domain optical coherence tomography (RTVue-100 OCT), and to compare the diagnostic accuracy of this parameter to that of parameters provided by the instrument software in European eyes. Methods:Retinal nerve fiber layer thickness (RNFLT) and macular GCC thickness parameters of 1 randomly selected eye of 177 white European patients (50 healthy, 28 ocular hypertensive, 33 preperimetric glaucoma, and 66 perimetric glaucoma eyes) were measured with an RTVue-100 OCT. Results:The RNFLT and GCC parameter values o...
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Interocular Retinal Nerve Fiber Layer Thickness Symmetry Value in Normal Young Adults

Journal of Glaucoma - Tue, 09/30/2014 - 11:00pm
Purpose:The aim of this study was to determine the normal range of interocular peripapillary retinal nerve fiber layer (RNFL) thickness symmetry value in young adults. Factors affecting interocular RNFL thickness symmetry were also investigated. Materials and Methods:Both eyes of 241 ophthalmologically and neurologically normal subjects were scanned using optical coherence tomography (200×200 optic disc cube protocol). The effect of ocular cyclotorsion on interocular RNFL thickness symmetry was determined and mathematically accounted for. Symmetry value between the right and left RNFL thickness values was calculated. Linear regression analyses were used to identify correlations between the corrected interocular symmetry value and interocular differences in refractive error, axial length, ...
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Upper Eyelid Tarsoconjunctival Flap for the Treatment of Ahmed Valve Plate Exposure

Journal of Glaucoma - Tue, 09/30/2014 - 11:00pm
Conclusions:Upper eyelid tarsoconjunctival flap is a useful option to cover exposed valvular plates in patients where traditional methods have failed. (Source: Journal of Glaucoma)
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Delayed Topiramate-induced Bilateral Angle-Closure Glaucoma

Journal of Glaucoma - Tue, 09/30/2014 - 11:00pm
Conclusions:This case provides evidence of delayed bilateral angle closure from topiramate and raises questions as to the cellular mechanism of topiramate-induced angle closure, both immediate and delayed. (Source: Journal of Glaucoma)
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High Intraocular Pressure After Carbamazepine and Gabapentin Intake in a Pseudoexfoliative Patient

Journal of Glaucoma - Tue, 09/30/2014 - 11:00pm
Conclusion:This is the first reported case of a large increase in IOP within hours after carbamazepine and gabapentin intake in a pseudoexfoliative eye. (Source: Journal of Glaucoma)
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Retinal Nerve Fiber Layer Volume Measurements in Healthy Subjects Using Spectral Domain Optical Coherence Tomography

Journal of Glaucoma - Tue, 09/30/2014 - 11:00pm
Purpose:To report retinal nerve fiber layer (RNFL) volume measurement using spectral domain optical coherence tomography (SD-OCT). We determined the characteristics and effecting factors of the RNFL volume in healthy eyes. Methods:Eighty-six eyes from 86 healthy volunteers were included. All participants underwent 3D-disc scanning using SD-OCT. We developed a computer program using Matlab software to extract RNFL thickness values from colored topographic RNFL thickness map. Total average, quadrant, and clock-hour RNFL volume were automatically calculated between 2.5 and 5 mm diameter circles using the length, width, and height of each pixel derived from the RNFL thickness map. Results:The mean total RNFL volume was 1.478±0.124 mm3 and RNFL volume profiles showed double-hump patterns. RNFL...
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