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Stem cell transplantation is a promising strategy for restoring eyesight resulting from corneal damage, but tissue grafts must contain a high percentage of stem cells for clinical success.
Health news and commentary from around the Web, gathered by the ALLMedPage Today staff
An international team of neuroscientists has shown that a person's ability to see fine visual detail can be sharpened by simply staring for a few seconds at a rapidly flickering display.
Study shows potential of assistive technology to improve quality of life for the visually impaired.
In a first of its kind study, Mount Sinai researchers are using optimal coherence tomography (OCT) angiography to look at the earliest stages of glaucoma and identify characteristic patterns of...
By peering into the eyes of mice and tracking their ocular movements, researchers made an unexpected discovery: the visual cortex - a region of the brain known to process sensory information ...
St. Jude Children's Research Hospital researchers report a topotecan-based chemotherapy regimen should be considered front-line therapy for patients with advanced bilateral retinoblastoma; an eye...
A well-known rheumatoid arthritis medication containing the active agent adalimumab, a therapeutic human monoclonal antibody, is also effective for treating non-infectious uveitis, a rare eye...
This article provides a brief summary of anatomy, purpose, and disorders of the cerebellum, also offering tips on preserving brain health.
Doctors discuss a rare case of a patient who died from Zika virus and the possibility of transmission to a second patient via contact with sweat and tears.
Purpose: To evaluate clinical parameters and their relationship to the presence of a relative afferent pupillary defect (RAPD).
Materials and Methods: Retrospective chart review of 672 consecutive patients who presented to the Glaucoma Service at Wills Eye Hospital from January 1 through May 29, 2012. Swinging flashlight method (SFM) was used to test for RAPDs. Records of visual acuity, intraocular pressure (IOP), disc-damage likelihood scale (DDLS), cup/disc (C/D) ratio, visual field mean deviation (MD), optical coherence tomography (OCT), and Heidelberg retinal tomography (HRT) asymmetries were examined. We measured the prevalence of RAPDs as clinical asymmetries increase, calculated cut-off points for clinical asymmetries that optimized sensitivity and specificity in detecting RAPDs, a...
Conclusions: We determined progression rates for untreated healthy and under treatment OHT and glaucoma eyes with the Avanti RTVue-XR optical coherence tomography. We found that an average RNFLT progression rate faster than −1.5 μm/y, and an average GCC progression rate faster than −1.3 μm/y are strongly suggestive for uncontrolled glaucomatous progression. Detection of uncontrolled structural progression with trend analysis may assist the early detection of fast progressors. (Source: Journal of Glaucoma)
Purpose: To compare intraocular pressure (IOP) measurement using the Goldmann applanation tonometry (GAT) without fluorescein, with fluorescein strips, with fluorescein droplets, and IOP measurement with Tono-Pen Avia (TPA).
Patients and Methods: This was a prospective comparative clinical analysis. It was performed in clinical practice. The study population consisted of 40 volunteer patients, 1 eye per patient. All patients who were 18 years and older having routine ophthalmological examination were eligible to participate. Active corneal abrasions and/or ulcers, previous glaucoma surgery, or prostheses interfering with GAT measurement were excluded. GAT IOP was measured first without fluorescein, then with fluorescein strip, then with fluorescein droplet, and finally with the TPA device...
Conclusions: The results provide evidence that, although slower than controls, patients with glaucoma were able to accomplish natural actions efficiently even when the task required discrimination of small structurally similar objects (nuts and screws in the model-building task). Their difficulties were reflected in longer fixation times and more head and eye movements compared with controls, presumably to compensate for lower visibility when objects fell in the part of their visual field where sensitivity was reduced. (Source: Journal of Glaucoma)
Conclusions: GCC measurements were more efficient than cpRNFL measurements in detecting preperimetric glaucomatous damage. This finding could be an aid to an early diagnosis. (Source: Journal of Glaucoma)
Conclusions: Trab with mitomycin produces satisfactory intraocular pressure control over time. However, several risk factors influence the efficacy of the surgical procedure. Our data show that there seems to exist an additive effect among risk factors with similar pathophysiology. (Source: Journal of Glaucoma)
Conclusions: Combined approach to trabeculectomy and phacoemulsification resulted in greater myopic RPEs that were expectedly greater than those found in the phacoemulsification group. (Source: Journal of Glaucoma)
Conclusion: Approximately 1 in 5 people with primary glaucoma were blind. Male sex, ethnicity and deprivation were strongly associated with blindness. Services for glaucoma need to improve in Nigeria, focusing on poor communities and men. (Source: Journal of Glaucoma)
Purpose: To perform a longitudinal analysis on the association of corneal haze with intraocular pressure (IOP) in eyes with primary congenital glaucoma (PCG) over 3 years.
Patients and Methods: Charts of all patients diagnosed with glaucoma of childhood from 2002 to 2012 at our institution were retrospectively reviewed. Inclusion criteria were age 18 years and below, plus elevated IOP or characteristic clinical signs. Exclusion criteria were eyes with secondary glaucoma or corneal haze not from PCG and patients with prior ocular surgery or incomplete follow-up.
Results: Of 79 eyes with childhood glaucoma during this period, 36 eyes had PCG [25 patients; 15 male (60.0%), 14 bilateral (56.0%)]. Eighteen eyes (13 patients) presented with corneal haze, whereas 18 eyes (12 patients) did not. ...