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Catalyst for a Cure 2016 Research Progress

Video progress report from the Catalyst for a Cure researchers; this collaborative research effort is designed to accelerate the pace of discovery toward better treatments and ultimately a cure for glaucoma.

Categories: News

Hydrogels can put stem cells to sleep

medicalnewstoday eye health - Wed, 02/10/2016 - 10:00am
Unlike normal cells, stem cells are pluripotent -- they can become any cell type, which makes them powerful potential treatments for diseases such as diabetes, leukemia and age-related blindness.
Categories: News

Researchers discover a genetic mutation that prevents diabetes complications

medicalnewstoday eye health - Wed, 02/10/2016 - 7:00am
A number of complications are associated with diabetes, but they are more prevalent in some patients than in others.
Categories: News

Using the physics of your perfect pancake to help save sight

medicalnewstoday eye health - Mon, 02/08/2016 - 3:00am
Understanding the textures and patterns of pancakes is helping UCL scientists improve surgical methods for treating glaucoma.
Categories: News

'Smart' lens could predict risk of glaucoma progression

medicalnewstoday eye health - Mon, 02/08/2016 - 2:00am
A 'smart' contact lens that can monitor eye pressure in glaucoma patients 24 hours a day has proven effective for identifying which patients are at risk of disease progression.
Categories: News

Potential new approaches to treating eye diseases

medicalnewstoday eye health - Fri, 02/05/2016 - 5:00am
Potential new approaches to treating eye diseases such as age-related macular degeneration (AMD) are described in a new study, "IL-33 amplifies an innate immune response in the degenerating...
Categories: News

Mature drivers favor checks on over 70s, new study finds

medicalnewstoday eye health - Fri, 02/05/2016 - 5:00am
The majority of older drivers are in favour of tighter rules on checking the health and suitability of over-70s to drive - even if those checks could take them off the road themselves - according...
Categories: News

Patients with macular degeneration show improvement with high-dose statin treatment

medicalnewstoday eye health - Fri, 02/05/2016 - 4:00am
Researchers at Massachusetts Eye and Ear/Harvard Medical School and the University of Crete have conducted a phase I/II clinical trial investigating the efficacy of statins (cholesterol-lowering...
Categories: News

Dr. Stuart McKinnon Awarded 2016 Shaffer Prize for Research

For his research project to determine whether therapies can be designed to modulate the immune system to prevent vision loss and blindness in glaucoma patients, Stuart J. McKinnon, MD, PhD was awarded the 2016 Shaffer Prize for Innovative Glaucoma Research.

Categories: News

Dr. Stuart McKinnon Awarded 2016 Shaffer Prize for Research

For his research project to determine whether therapies can be designed to modulate the immune system to prevent vision loss and blindness in glaucoma patients, Stuart J. McKinnon, MD, PhD was awarded the 2016 Shaffer Prize for Innovative Glaucoma Research.

Categories: News

Iridocorneal Endothelial Syndrome in a 14-Year-Old Male

Journal of Glaucoma - Sun, 01/31/2016 - 11:00pm
We report a case of iridocorneal endothelial in a 14-year-old boy who did not yet have ocular hypertension or glaucoma. (Source: Journal of Glaucoma)
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Bilateral Subretinal Fluid Mimicking Subretinal Neovascularization Within 24 Hours After Selective Laser Trabeculoplasty

Journal of Glaucoma - Sun, 01/31/2016 - 11:00pm
Conclusions: The sudden onset of loss of vision and the development of subfoveal SRF within 24 hours of SLT strongly suggests cause and effect. This previously unreported clinical entity of bilateral SRF within 24 hours of SLT may be secondary to an intraocular inflammatory cascade, similar to previous hypotheses regarding 3 cases of cystoid macular edema post-SLT. Given the dramatic initial loss of vision and compromised long-term visual outcome, clinicians and patients need to be informed of this new clinical entity of SLT associated with SRF and permanent retinal pigment epithelial changes. (Source: Journal of Glaucoma)
Categories: News

A Novel KERA Mutation in a Case of Autosomal Recessive Cornea Plana With Primary Angle-Closure Glaucoma

Journal of Glaucoma - Sun, 01/31/2016 - 11:00pm
Conclusions: The mutation that we report here leads to the deletion of a conserved amino acid (p.Phe125del) from the third LRR motif of the keratocan protein, which might lead to an abnormal tertiary structure of the protein, thereby leading to the disease. (Source: Journal of Glaucoma)
Categories: News

Drug-induced Bilateral Secondary Angle-Closure Glaucoma: A Literature Synthesis

Journal of Glaucoma - Sun, 01/31/2016 - 11:00pm
Conclusions: Several compound preparations were implicated in drug-induced bilateral 2° ACG. Treating physicians should be aware that some forms of recreational drug use, which the patient may not admit to, could contribute to this vision-threatening side effect. (Source: Journal of Glaucoma)
Categories: News

Plasma Homocysteine, Serum Folic Acid, Serum Vitamin B12, Serum Vitamin B6, MTHFR, and Risk of Normal-Tension Glaucoma

Journal of Glaucoma - Sun, 01/31/2016 - 11:00pm
Conclusion: NTG is not associated with elevated plasma tHcy, serum folic acid, serum vitamin B12, serum vitamin B6, and MTHFR C677T genotype. (Source: Journal of Glaucoma)
Categories: News

Diagnostic Abilities of Variable and Enhanced Corneal Compensation Algorithms of GDx in Different Severities of Glaucoma

Journal of Glaucoma - Sun, 01/31/2016 - 11:00pm
Conclusion: In scans satisfying the manufacturer-recommended quality parameters, which were significantly greater with ECC than VCC algorithm, diagnostic abilities of GDx ECC and VCC in glaucoma were similar. (Source: Journal of Glaucoma)
Categories: News

Plateau Iris in Primary Angle Closure Glaucoma: An Ultrasound Biomicroscopy Study

Journal of Glaucoma - Sun, 01/31/2016 - 11:00pm
Conclusions: Patients with plateau iris had significantly shallow central ACD when compared with those with pupillary block and normal eyes. After laser peripheral iridotomy, about a third of PACG eyes had plateau iris. This is clinically important because these patients can develop synechial angle closure and should be followed up closely. (Source: Journal of Glaucoma)
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Structural Differences in the Optic Nerve Head of Glaucoma Patients With and Without Disc Hemorrhages

Journal of Glaucoma - Sun, 01/31/2016 - 11:00pm
Purpose: The aim of the study was to evaluate differences in planimetry, optic nerve parameters, and visual field (VF) indices in glaucomatous eyes with a disc hemorrhage (DH), their contralateral counterparts without DH, and normal controls. Patients and Methods: We retrospectively reviewed the records (from 1995 to 2013) of 44 glaucoma subjects with unilateral DH and 50 normal controls. In the DH group, 33 had bilateral fundus photos for planimetric analysis (Cyoptique GL), 15 had spectral domain-optical coherence tomography (SD-OCT), 15 had VF indices (Humphrey Visual Field Analyser), and 39 had ≥5 perimetry outputs for progression analysis (Progressor). Results: Structurally, planimetric analysis revealed that the eye with DH had a larger cup-disc ratio, more significantly in the v...
Categories: News

Endophthalmitis Trends and Outcomes Following Glaucoma Surgery at a Tertiary Eye Care Hospital in Saudi Arabia

Journal of Glaucoma - Sun, 01/31/2016 - 11:00pm
Purpose: To compare the incidence, microbial profile, management and outcomes of endophthalmitis after glaucoma drainage implant (GDI), or trabeculectomy over 2 separate time periods before and after the year 2000. Methods: A chart review was performed for patients with endophthalmitis after trabeculectomy (trabeculectomy group) or GDI group between 1983 to 1999 (group 1) and 2000 to 2011 (group 2) at a tertiary care hospital. Data were compared between groups and time periods. Results: There were 56 cases of endophthalmitis after trabeculectomy in group 1 and 17 cases in group 2. After GDI, there were 10 cases of endophthalmitis in group 1 and 1 case in group 2. The incidence of endophthalmitis after GDI decreased significantly from 0.0105% to 0.00074% in groups 1 and 2, respectively (P...
Categories: News

Icare ONE Home Tonometry in Children With and Without Known Glaucoma

Journal of Glaucoma - Sun, 01/31/2016 - 11:00pm
Conclusions: Icare ONE home tonometry seems feasible in a small number of children. Normal eyes demonstrated smaller daily IOP ranges than glaucomatous eyes. Normal eyes were also more likely to show a relative early morning IOP peak and a late evening IOP trough. It is likely that the limited sampling in this study limits its generalizability to all children with glaucoma or to normal children. (Source: Journal of Glaucoma)
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